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Supplementary information Supplementary Figures 1-18 and Supplementary Tables 1-5

No hormonal effects

The structural S protein is approximately 180200 kDa in size and is made up of an extracellular N-terminal domain, receptor-binding domain (RBD) in the S1 subunit, an intracellularly located C-terminal domain, transmembrane (TM) domain, and heptad repeat 1 (HR1) and HR2 located in the S2 subunit [20]

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Clin Transl Med

Microcomedones (acne lesions that were already forming under the surface) come up faster during the first 2 to 4 weeks of use