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Maternal Immune Activation Therapeutics Maternal immune activation (MIA), or the initiation of inflammatory pathways during pregnancy, has been associated with the pathogenesis of neurodevelopmental disorders, including ASD [45,46,47]

ROS can initiate different modes of cell death through their oxidative effects on specific redox-sensitive proteins

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This phase establishes whether the drug is safe enough to proceed to efficacy testing, operating under the core ethical principle of nonmaleficence to minimize potential harm to human subjects

The HCC827, gefitinib-sensitive human lung adenocarcinoma cell line was obtained from the American Type Culture Collection (ATCC)