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Alleviating TMAO to treat IBD An increasing amount of epidemiological evidence suggests that many underlying factors, including high altitude, hypoxia, urbanization, pollution, physical activity, nutrition, and medication, play important roles in the development and progression of IBD (155)

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Immunotherapy causes a multitude of immune-related phenomena, such as lichenoid reactions or vitiligo, as well as reactivation of pre-existing skin conditions (e.g., psoriasis)