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Journal Franais d'Ophtalmologie, 38(1), e3

These immunomodulatory functions of microbiota-derived metabolites could therefore provide an interesting mechanistic link between the microbiome and its influence on ICB outcome

10.1113/JP271229 J

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Hypoxia can also directly increase fatty acid synthesis by upregulating key enzymes such as fatty acid synthase (FAS) [12] and can increase flux through additional metabolic pathways that fuel lipid synthesis, including reductive carboxylation of glutamine [13]

The mechanisms by which drugs induce melanin synthesis remain unclear