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Extracellular Signal Regulated Protein Kinase (ERK) pathway was inferred as the target of compound 374 , which acted against anomalous activated cells of the ERK-MAP pathway without side-effects (Sasaki et al
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The mTORC1 and mTORC2 respond to growth factors, but only mTORC1 is influenced by glucose and amino acids (Jewell and Guan, 2013)
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