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Serum H 2 S levels were diminished in patients with COPD-related PH and H 2 S levels were negatively correlated with PASP, indicating that H 2 S may play an important role in the pathogenesis of COPD-related PH (Yuan et al., 2019

[13] Jilani T, Iqba MP

While this might partly subcellular compartmentation and the lower reducing power (higher redox potential) of ascorbate compared to glutathione, NADH, and NADPH, it also points to efficient co-operation between the various isoforms of the three reductases