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IL-1 is a potent pro-inflammatory cytokine that can initiate and amplify lung inflammation and has been associated with acute lung injury by enhancing the recruitment of neutrophils, monocytes, and lymphocytes, precipitating fibrosis through activation of resident pulmonary fibroblasts to synthesize collagen and fibrin 69

Comparative trials, such as those juxtaposing the efficacy of ozone prolotherapy and intra-articular hypertonic saline, found both modalities to be therapeutically analogous [45]

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(1997) [50] suggested that the proportion of gut-associated bacteria is higher than that of the overall microbial community in various species of arthropods

Esposito S, Sorbo S, Conte B, Basile A

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