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J Biol Chem 265:2043720442 Downward J, Graves JD, Warne PH et al (1990) Stimulation of p21ras upon T-cell activation

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More specifically, dopamine binding to a dopamine receptor triggers a conformational shift that allows a guanine exchange factor to exchange a guanosine diphosphate for the guanosine triphosphate bound to the subunit of the heterotrimeric G-protein

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