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The honest answer, based on the available research, is that the effect is real and directionally consistent with the physiology, but modest under ordinary circumstances not the dramatic swing implied by many unsourced blog claims

Conditioned Reflexes: An Investigation of the Physiological Activity of the Cerebral Cortex

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The combined-receptor stimulation produces additive metabolic effects compared with either component alone, as documented across the published Phase 1, Phase 2, and Phase 3 clinical-trial program

Chapter 5: The apoB/apoA-I Ratio is a Strong Predictor of Cardiovascular Risk