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14 , 15 , 16 These factors are known to stimulate the activation of intracellular STAT proteins, which are phosphorylated and dimerized, and subsequently translocated to the nucleus for the transactivation of several genes involved in numerous cellular processes

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During this important time of exposure to microbes, microbes help the hosts immune system development, nutritional absorption, growth performance and inhibition of pathogenic bacteria (Belkaid and Hand, 2014