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Elevated levels of G6PD in ATMs can cause obesity-related inflammation ( de novo lipogenesis (DNL) which promotes hepatic steatosis and insulin resistance ( via NOXs, leading to liver damage and insulin resistance ( Carbohydrate kinase-like protein (CARKL), also known as sedoheptulokinase (SHPK), is a carbohydrate kinase catalyzing the phosphorylation of sedoheptulose to S7P (Figure 2)

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Other candidate flow sensors that have been proposed include the glycocalyx and the platelet endothelial cell adhesion molecule-1/cadherin/vascular endothelial growth factor receptor-2 complex [23, 2934]

10.1111/j.1474-9726.2011.00700.x [DOI] [PMC free article] [PubMed] [Google Scholar] De Vitis M, Berardinelli F, Sgura A (2018) Telomere length maintenance in cancer: at the crossroad between telomerase and alternative lengthening of telomeres (ALT)

DAQs could conjugate with and modify Cys95 and Cys253 residues of Parkin protein, leading to its insolubility, as revealed in post-mortem patient brain samples and in PD models in vivo [82, 134]