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These eight vitamin substances include thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), vitamin B6, biotin (B7), folate (found in leafy greens), and vitamin B12

doi: 10.1073/pnas.95.15.8880

Ruka, Molecular and biochemical testing in stage III melanoma: multimarker reverse transcriptase-polymerase chain reaction assay of lymph fluid after lymph node dissection and preoperative serum lactate dehydrogenase level

In the context of skincare, it is widely recognized for its melanin-inhibiting properties

Nat Prod Res 35(2):350353

Results typically become visible around week 4 to 6, with significant improvement by month 3