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The MAPK pathway consists of a phosphorylation series: MAPKKKs activate MAPKKs, which in turn activate MAPKs, responsible for phosphorylating transcription factors that induce metal response genes (Li et al

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1 RNAs were isolated from cardiac tissues using a kit from Promega (Madison, WI, USA) and reverse-transcribed into cDNAs by using a cDNA synthesis kit from Invitrogen (Carlsbad, CA, USA)

10.26402/jpp.2021.3.06 61 StaalL.PlschT.Kunovac KallakT.Sundstrm PoromaaI.WertheimB.OlivierJ

doi: 10.1074/jbc.M206835200, 54 GeD.NoakesP

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