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Oxidative stress was assessed by quantifying thiobarbituric acid (TBA) reactivity as malondialdehyde (MDA) equivalents and by determining the NO levels in the colon tissue

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Taskran et al.s (2018) [24] protocol consisted of multiple intraperitoneal injections of vitamin B12 for a week before testing the animals with PTZ injections, while Filiz et al.s (2021) [1] protocol was to affect kindling procedures, which consisted of subthreshold convulsion doses of PTZ combined with vitamin B12 administration for about a month

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