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Viral nsp12 could alter AA metabolism (especially of the branchedchain amino acids , BCAA), while nsp12, nsp7 , and nsp8 interactions with electron transport chain (ETC) and ribosomal proteins could potentially dysregulate mitochondrial respiration 39

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3 The 3 important clinical features that support a diagnosis of HS are typical lesions, typical locations, and relapses and chronicity (Box 2)

pylori infection compared with those with gastritis who were noninfected (156)

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