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The treatment is commonly available in subcutaneous injections, but alternative forms such as sublingual options have recently emerged

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We previously reported that endogenous MOTS-c translocates to the nucleus to directly regulate adaptive nuclear gene expression in response to cellular stress 17

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Injectable hydrogels Injectable hydrogels are stimuli-responsive polymeric networks designed to undergo sol-to-gel transitions under physiological conditions, thereby enabling localized and sustained drug delivery via minimally invasive SC administration [44]