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Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells

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Cheng, Y., Zak, O., Aisen, P., Harrison, S

1 Introduction Within the field of aging research, the intricate relationship between sleep architecture and metabolism has emerged as a significant contributor to age-related health changes and pathological aging conditions, such as Alzheimers disease and dementia (Zhang W