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Taking metformin can lead to vitamin B-12 deficiency, as it can lead to bacterial overgrowth and alter the bodys ability to efficiently uptake B-12 within the small intestine

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Other Factors: Certain genetic factors, such as mutations in genes involved in vitamin B12 metabolism, can predispose individuals to vitamin B12 deficiency

Red liquid (vitamin B12) in a disposable syringe with a needle and in a glass ampoule on a white background

Contraindications and Precautions Do NOT use AOD-9604 if you: Are pregnant, trying to conceive, or breastfeeding (no safety data in pregnancy/lactation) Have active cancer or history of malignancy (peptide effects on existing cancer unknown) Are under 18 years of age (pediatric safety not established) Have known hypersensitivity to peptides or benzyl alcohol (in bacteriostatic water) Have severe kidney or liver disease without physician clearance Use with caution and enhanced monitoring if you have: Diabetes or glucose metabolism disorders (monitor blood sugar closely despite no expected impact) Cardiovascular disease (comprehensive cardiac evaluation recommended) Thyroid disorders (monitor thyroid function during therapy) History of migraines (may increase headache frequency in susceptible individuals) Drug Interactions Limited formal drug interaction studies exist for AOD-9604

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