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The short half-life (12 min in humans) results from dipeptidylpeptidase-IV (DPP-IV) proteolysis by which the N-terminal dipeptide is rapidly removed, inactivating GLP-1
Depending on the severity of the disease, you use one, the other or both
Cryan et al., 2019
Originally developed to manage type 2 diabetes, GLP-1 medications are now reshaping how we think about weight loss, appetite control, and metabolic health
Macintosh MCM, Fleming KM, Bailey JA, Doyle P, Modder J, Acolet D, et al
