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After 7 weeks, the mandibular first molars in the P and PH groups were ligated with sterile 3 0 silk sutures to establish a periodontitis model

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(4) Anti-freezing is required, and precipitation can occur after long-term storage

Conflicts of Interest: The authors declare that they have no conflicts of interest to report regarding the present study

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By targeting the HIF-1 gene and regulating its stability and activity in hypoxic conditions, gene editing can effectively alleviate the pathological manifestations of HAPH [115]