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Researchers can request the COA before purchase and verify that the lot number on the COA matches the lot number on the vial received

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Water softening is a process that aims to remove minerals such as calcium, magnesium, and sometimes iron ions that create "hardness" in water

The technology used for these tests cannot detect peptide structures

Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist

Acknowledgements The authors would like to acknowledge all members of the Obesity Integrated Responsibility Unit (CRI-O) group