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Hemoglobinopathies Sickle cell disease SCD is caused by a point mutation in the Hb subunit chain and shows multiple clinical manifestations and early mortality, particularly if the individual is homozygous for the mutation or untreated (80)

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to regulate microbial composition (Reverter et al., 2018)

doi: 10.1007/s003950050167

Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties

Concurrent medications and meal patterns can also inform timing choices