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Besides, it markedly diminished gene expression of inducible nitric oxide synthase (iNOS) assessed by real time PCR technique, as well as protein levels of IL-1, IKK, NF-B, NLRP3 and galectin 3 emphasizing its potent anti-inflammatory effects

10.1007/s00299-010-0939-0 211 ZhangM.GongM.YangY.LiX.WangH.ZouZ

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The same combination had minimal effects on normal PBMC (Fig

This phenotype was accompanied by accumulation of intracellular ferrous iron and lipid peroxides and the extracellular release of malondialdehyde, all indicative of redox stress, and increased levels of lactate dehydrogenase in the culture supernatant, indicating enhanced cell injury