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What the Research Shows A 2022 NIH study identified caffeine, sodas, and energy drinks as modifiable lifestyle factors that may impair spermatogenesis (the process of sperm formation)

Exceeding these thresholds causes muscle distension, pain, and reduced absorption efficiency as the tissue cannot accommodate the fluid volume

Yang X, Xiang J, Su W, Guo J, Deng J, Tang L, Li G, Liang Y, Zheng L, He M, et al

Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity

These effects make sense given MOTS-cs known ability to increase nitric oxide bioavailability (through AMPK) and reduce inflammation, both of which are critical for healthy blood vessels
doi: 10.1039/d0na00676a 341 KonoshenkoMYLekchnovEAVlassovAVLaktionovPP
