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What the Research Shows A 2022 NIH study identified caffeine, sodas, and energy drinks as modifiable lifestyle factors that may impair spermatogenesis (the process of sperm formation)

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Exceeding these thresholds causes muscle distension, pain, and reduced absorption efficiency as the tissue cannot accommodate the fluid volume

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Yang X, Xiang J, Su W, Guo J, Deng J, Tang L, Li G, Liang Y, Zheng L, He M, et al

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Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity

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These effects make sense given MOTS-cs known ability to increase nitric oxide bioavailability (through AMPK) and reduce inflammation, both of which are critical for healthy blood vessels

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doi: 10.1039/d0na00676a 341 KonoshenkoMYLekchnovEAVlassovAVLaktionovPP

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