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Others may not be able to use them because of other medications, health history, or side effects

These compounds yielded significant improvements in potency, selectivity, and pharmacokinetic properties while maintaining key interactions with JNK3

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Figure 2 6 Conclusion It is obvious that not all Cys residues are the same and that the Cys residues that confer signaling properties to proteins are unique because of their position in the protein, the surrounding amino acids, protein cellular localization, and its redox environment