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doi: 10.1136/annrheumdis-2017-212763 69 LiotFBoval-BoizardBWeillDKuntzDWautierJL
Interestingly, inhibition of different enzymes in the TCA cycle results in different regulation of amino acid metabolism, although common features are evident (Ryan et al., 2021)
Isolated Complex II Deficiency Disease The pathogenic variants affecting complex II genes results in mitochondrial dysfunction
Response time varies, though
At this stage, the therapeutic efficacy of Rg1 remains to be established by further clinical validation, although the initial findings are encouraging
Ding, Jinhui
