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Metabolic modulators such as metformin and pioglitazone are receiving more attention in the context of ASD, not only as supplementary therapies aimed at reducing the metabolic side effects of conventional medication, but also as potential primary interventions

The FDA does not approve compounded medications for safety, quality, or manufacturing

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doi: 10.1038/s41420-025-02415-x 145 Ocaa-GuzmanRTorre-BouscouletLSada-OvalleI

IGF-1 prevents ANG II-induced skeletal muscle atrophy via Akt- and Foxo-dependent inhibition of the ubiquitin ligase atrogin-1 expression

doi:10.2337/dc20-S002 American Diabetes Association