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Variola proteins that may be hindered include those involved in viral replication, specifically, encoded viral DNA topoisomerases, and evasion of host immunologic defenses

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Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

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demonstrated in vitro that T cells are highly sensitive to glutamine levels and that reducing the glutamine concentration inhibits T cell proliferation [30]

Acetaminophen-induced nephrotoxicity: pathophysiology, clinical manifestations, and management