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Hyperlipidemia increases serum hepcidin, which can be inhibited by the intervention of natural compound tetramethylpyrazine (TMP), and TMP may lower hepcidin expression by inhibiting the STAT3 signaling pathway

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3.3 Limited persistence of CAR-T cells The clinical responsiveness of CAR-T cells is related to the in vivo expansion ability and long-term persistent activity of functional CAR-T cells (82)