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Manipulation of plant tolerance to herbicides through co-ordinated metabolic engineering of a detoxifying glutathione transferase and thiol cosubstrate

Reactions included nausea, vomiting, chills, low blood pressure, difficulty breathing , and in some cases, possible bloodstream infection

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The situation appears to be more complex for cocaine, as CB1 antagonists or knockout do not prevent self-administration of this drug (Cossu et al., 2001