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Sunitinib has also been shown in tumor-bearing mice and patients with metastatic renal carcinoma to lower the number and efficacy of Tregs [89]

Furthermore, a study on the Blood-Brain Barrier (BBB) permeability of CAs bioactive componentsasiaticoside, madecassoside, and asiatic acidrevealed that these compounds have a high capability to cross the BBB

et al., + /NAD(P)H redox balance by NQO1-mediated metabolism of -lapachone or other redox active quinones may have therapeutic potential via the ability to generate NAD + and stimulate sirtuin and PARP activities (Figure 3)

Emp-induced alterations of tight junction protein expression and disruption of the blood-brain barrier

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Traditional Mongolian medicine emphasises the unity between human beings and the natural environment, explaining the interconnection and interaction between the activities of organs in the body and the environment (Figure 6) (Kletter et al., 2008)