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Beyond vascular [79,80] and immune functions [81,82,83], NO contributes to central and peripheral sensitization by modulating excitatory neurotransmission and interacting with cyclic GMP pathways [84,85,86]
Even under these circumstances, we believe that the temporal distortion is introduced at stages downstream of surface receptor activation and that the cell would still benefit by maintaining a faithful temporal coupling between the input ligand waveform and the upstream molecular signal that it elicits
& Nakamura, Y
On the other hand, Ru1-Ru3 significantly induced the depletion of ATP (ATP), causing disturbance of energy generation
Why Researchers Choose DSIP Endogenous Neuropeptide: Provides a physiologically relevant model for sleep research
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