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167 , 168 Currently, CD38 antibodies are also combined with PIs such as carfilzomib and bortezomib, however the exact mechanisms by which these combinations exert their efficacy are less clear than combinations with IMiDs

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References: Cherney K

In diet-induced obesity models, this inhibition has been observed to reduce white fat accumulation and promote lipolysis, effectively reprogramming metabolic pathways toward enhanced energy expenditure

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