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L-carnitine also may help reduce lactic acid accumulation and support a higher lactate threshold, but most importantly, it may help reduce mental fatigue

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Tobacco-Induced Pigmentation Nicotine and benzopyrenes in cigarette smoke directly stimulate melanocytes in the labial mucosa, producing a progressive darkening known clinically as smoker's melanosis

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[15] However, more research is needed to determine the complex interaction between genetic makeup and overall UV exposure

In addition, 23 patients had more than one recurrent nevus occurring at separate locations and 6 patients had multiple recurrences of the same lesion, resulting in a total of 357 biopsies