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Material and Methods 4.1

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82100769), GuangDong Basic and Applied Basic Research Foundation (2024A1515011237), Science and Technology Planning Project of Zhanjiang (2021A05064, 2022A01158), Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases (2022B1212030003), and National Clinical Key Specialty Construction Project (Institute of Nephrology, Affiliated Hospital of Guangdong Medical University)

Oxaloacetate (OAA) can be transaminated to aspartate by aspartate transaminase which also provides a means for nitrogen trafficking

Regarding the connection between GSH and cell death, a major issue remaining to be resolved concerns the type of cell death induced by GSH depletion