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Diarrhoea is an uncommon side effect of vitamin B12 supplementation, listed as a rare adverse reaction in UK product information for both oral and injectable preparations

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[DOI] [PMC free article] [PubMed] [Google Scholar] Andres 2008 Andres E, Vogel T, Federici L, Zimmer J, Kaltenbach G

Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels

Injections may be used to quickly and effectively restore B12 levels, particularly in cases where malabsorption is a concern