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Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone

[DOI] [PMC free article] [PubMed] [Google Scholar] Kim, C.Y

Raf-1, B-Raf, VEGFR-1-3 and FLT3) inhibitor, in hepatocellular carcinoma (HCC) cells, and additionally reported a case of prolonged regression of a HCC patient upon combination treatment with IV high-dose VitC and sorafenib [116]

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In paclitaxel-resistant nonsmall cell lung cancer (NSCLC) cells, curcumin enhances sensitivity to paclitaxel by inducing S-phase cell cycle arrest and reducing metastasis-associated protein 1 (MTA1) expression through miRNA-30cmediated regulation (Lu et al., 2017)

Loss of epithelium-specific GPx2 results in aberrant cell fate decisions during intestinal differentiation