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Although initial clinical assessment pointed toward a potential hematologic malignancy, comprehensive testing, including SPEP, reticulocyte count/fraction, serum folate, and serum vitamin B12, revealed only severe vitamin B12 deficiency, with a level of less than 150, with the presence of IF antibodies

Accurate dosing ensures consistent results across treatment cycles

Studied in models involving NNMT activity, NAD+-related biology, and metabolic pathway regulation

26 B12 present in food products requires gastric enzymes such as pepsin and stomach acid to detach it from protein, while supplemental forms of B12 are typically in an unbound state and do not require this process for absorption

Nucl Med Biol

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