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Additional quantification by PRM were performed on closely eluting VVVFIKPTC(GSH)PYC(O3)R and VVVFIKPTC(O3)PYC(GSH)R, when necessary

others with deeper pigmentation or higher oxidative stress may require more sessions

Discovery of Second generation reversible covalent DPP1 inhibitors leading to an Oxazepane Amidoacetonitrile based clinical candidate (AZD7986)