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mtDNA is required for a large amount of Fe2+, and iron ions in the mitochondria are mainly used for synthesis of haemoglobin and the Fe-S family, or are stored in mitochondrial ferritin [37, 87]

Tao S, Liu P, Luo G, Rojo de la Vega M, Chen H, Wu T, et al

doi:10.1021/bi902022n, PMID: 20070126 Yan Z, Garg SK, Kipnis J, Banerjee R (2009) Extracellular redox modulation by regulatory T cells
The route isnt a minor detail

Research suggests it may help restore insulin signalling, regulate ovarian hormone activity, and support ovulation in women with insulin-resistant PCOS

ChenGHuMWangX-CDuS-HChengZ-XXuJet al