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Dalam bentuk oral, glutathione umumnya dapat ditoleransi dengan baik, sedangkan penggunaan melalui injeksi menunjukkan tingkat toleransi yang lebih rendah
Curcumin restores rotenone induced depressive-like symptoms in animal model of neurotoxicity: assessment by social interaction test and sucrose preference test
For example: Low magnesium may contribute to restlessness and poor sleep

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Of the homozygous mutations most studied, a carrier of the homozygous T677T isoform produces 75% less methyl folate than someone without the mutation, and carriers of the homozygous C1298C isoform produces 17% less methyl folate (Table 1)
Morroni et al