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It has been demonstrated that pseudolaric acid B could reinforce iron input by increasing TFR thereby triggering ferroptosis in glioma cells (Wang et al., 2018)

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For brain homogenates, 0.2 ml of the preparation was diluted to 1 ml by the respiration buffer

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Sheridan KJ, Lechner BE, Keeffe GO, et al

84 Epigenetic alterations such as histone modifications (e.g., H3K9me3 loss) contribute to the upregulation of inflammatory genes and an imbalance in macrophage polarization, further reinforcing systemic inflammation