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Supplementing with vitamin B12 is generally considered safe, as there is a low risk of toxicity

The NOS part stands for Not Otherwise Specified

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Higher-dose oral B12 (e.g., 1000 g daily) is sometimes used but should only be considered under clinical supervision with appropriate monitoring, particularly in cases of malabsorption where intramuscular treatment remains the first-line approach in UK practice

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Some people struggle with weight loss because of underlying B12 deficiencies caused by diet or absorption issues