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Notably, the biological activity of the hydrolysis products is generally lower or negligible

Malpractice is determined by whether the physician deviated from the standard of care and caused harm

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Consistent with this interpretation, several cellular abnormalities have been reported in the DLPFC of schizophrenic patients, which represent an imbalance in excitatory and inhibitory neurotransmission (E/I imbalance) 23,24

Bioessays (2006) 28(6):60616.10.1002/bies.20423 67 WadaYLonnerdalB

At the same time, concern about their successful translation in clinical settings has arisen due to the disparity between the huge number of research publications on nanomedicines and their limited translation into clinics, as shown in Table 3, with the recent approval of Onivyde (liposomal irinotecan) and Vyxeos (liposomal daunorubicin plus cytarabine) [373]