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Despite the practical value of engineered BEMNs as drug delivery systems, their wide clinical applications currently remain largely limited

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DTPA was conjugated to poly(-glutamic acid) (PGA) to maintain the complexing agent concentrated on the intestinal mucosal surface, where enzyme inhibition and paracellular permeation enhancement are vital

In accordance with the above, the 48 displayed submicromolar phototoxicity against cancer cells, but efficiency of original squaraine dye was significantly smaller

These findings supported the conclusion that P-Mn/TI@mHSA exhibited a favorable safety profile and holds potential for clinical application

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