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Since B 12 deficiency results in MMA accumulation before B 12 reduction is seen in the serum [132], methylmalonic acid is a better indicator and preferred marker reflecting B 12 status before B 12 deficiency appears [120]

Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome

Its possible I would say

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Over time, high blood sugar levels can cause damage to the nervous system, while medications prescribed to maintain blood sugar levels can also lead to B12 deficiency