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[35] 1298AA is the "normal" homozygous, 1298AC the heterozygous, and 1298CC the homozygous for the "variant"

2017 Jun;56(3):521-528

Trials that found a benefit measured change at 4 to 12 weeks of daily, uninterrupted use judging it any sooner isn't a fair test

This p21/Nrf2 axis has been demonstrated to be a critical inhibitor of ferroptosis, and notably, this activation can occur through both p53-dependent and p53-independent mechanisms 40

REFERENCES 1 AndreassenM.RaymondI.KistorpC.HildebrandtP.FaberJ.KristensenL

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