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doi: 10.1016/j.semcancer.2019.06.006 88 UlanovskayaOAZuhlAMCravattBF

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References Center for Substance Abuse Treatment

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Hydroxocobalamin in Neo-B12 Injection is the precursor for the enzyme co-enzyme B12 and this reacts with the enzyme Methylmalonyl Coenzyme A mutase, an isomerase required for the conversion of methylmalonate to succinate, an important step in production of lipoprotein in myelin sheath tissue, which could cause neurological problems

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Clinical symptoms and hematology parameter which could have validated improvement in vitamin B12 levels by NASO B12 before and after treatment were not studied

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