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Jarrett JT, Berger EP, Lansbury PT Jr (1993) The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimers disease

Additional studies have pinpointed 58 DMRs in the prefrontal cortex of ASD patients, particularly associated with genes of the GABAergic system and brain-specific microRNAs (Nardone et al., 2017), suggesting that specific methylation changes in cortical neurons may underlie ASD-related neurodevelopmental abnormalities

Blood-brain barrier drug targeting: The future of brain drug development

[GSH] i was directly manipulated using either blockers of its synthesis, such as buthionine sulfoximine (BSO), or GSH cycle activators, such as sulforaphane (SFN) that enhances the expression of GSH synthetizing enzymes through the Nrf2 pathway activation

Yu C, Li P, Dang X, Zhang X, Mao Y, Chen X

Because GHK-Cu interacts with regenerative, collagen-related, antioxidant-support, and tissue-maintenance pathways, observed responses may reflect broader physiological-resilience and recovery-focused signaling mechanisms associated with these pathways
