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doi: 10.1042/BCJ20200240

Beckman et al., SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19, Cell Reports, doi:10.1016/j.celrep.2022.111573

The GSH antioxidant system initiates the metabolic reprogramming of activated T cells, helping T cells make up for their demand for acetyl-CoA and avoid T cell death-induced immune regulation disorder 35

doi: 10.4103/1008-682X.154991 85 HuoWLiHZhangYLiH

Prooxidants, such as O 2 and Asc, could re-reduce Fe 3+ (Cu 2+ ) to Fe 2+ (Cu 1+ ) and restore these ions in the game (Salehi et al., 2020)

In doing so, they reduce glycation by blocking the formation of Amadori products, methylglyoxal (MG) derivatives, and other glycated residues 3